Diagnostic criteria for chronic candida research
An unambiguous definition
Before any study of chronic candida (aka Candida-Related
complex, CRC) can be done, an unambiguous definition1
is required. Some books about this phenomenon
list so many symptoms as diagnostic
of the disorder that the end up with an overly broad definition
of what defines the disorder.
Restrictive, limited diagnostic criteria are necessary for
research purposes. There must be a gold standard that
definitively distinguished chronic candida from other,
I have been using the criteria below. They are
based on my contact with other patients, and accounts
written by practitioners. I don't believe they encompasses
all cases of chronic candida. However, most advocates for
the existence of the condition would agree that
a patient meeting these criteria definitely has the disorder.
- Presence of two or more gastrointestinal(GI)
symptoms of sufficient severity to cause a change
in diet or take medication,
lasting more that two months and not responding completely
to appropriate treatment.
Presence of fatigue and difficulty
concentrating("brain fog"), severe enough to substantially
reduce or impair normal functioning.
Use of antibiotics for a cumulative total of greater than
two months of daily use, with some use falling immediately
prior to the development of symptoms.
Absence of any known general medical disorder
that would sufficiently account for these symptoms,
- Constipation, diarrhea, or obstipation
- Indigestion/sour stomach
- Food sensitivities
A significant, lasting positive response to both of
the following treatments.
- Crohn's disease
- Celiac sprue
- Small bowel bacterial overgrowth
- Hypoadrenalism(Addison's disease)
- One or more prescription antifungal (i.e. nystatin, diflucan,
- The dietary elimination of sugar(candy, cake, ice cream)
and highly refined carbohydrates(potato chips and other
high-calorie snack foods with hydrogenated fat).
- Bennet JE MD "Searching for the yeast connection"
New England Journal of Medicine 323(25):1766-7,
Dec. 20 1990
Last updated on: 2010-11-07
Information on this site, including comments on medical treatments, is
not intended as medical advice to visitors. It should be
evaluated critically and should not take the place of
medical advice from a licensed healthcare professional.