Author's Bio

Website Origin

This site began in March of 1998 to share what I read in the medical literature on the gastrointestinal microflora and probiotic bacteria. I had been following this subject since 1995, and I think damaged GI microflora might be responsible for unexplained GI symptoms and systemic symptoms, such as fatigue. I've suffered from this since taking tetracycline for a year in 1987. Probiotics, anti-candida medication, and avoiding sugar have been the only things that help.

In September of 2000, I added a "voluntary patient database" for visitors to share their own experiences with "chronic candida" symptoms, any treatments they have tried, their results, and experiences with specific practitioners.

My experience

I gradually developed severe fatigue and GI symptoms at age 18 while taking the antibiotic tetracycline for a year. It interfered with my schoolwork until I was no longer in school at all (I had been a "A" student). This led to a period of depression, all the while with no medial diagnosis (I was told my GI symptoms and fatigue were depression-related).

The depression abated after 18 months, but the GI symptoms and disabling fatigue remained. Several physicians (including gastroenterologists) told me there was no medical explanation for my symptoms. I struggled to survive financially, with no idea what was wrong with me. After being sick for four years, I began to explore alternative medicine and "fringe" diagnosis, such as unusual allergies.

Eventually, in 1992, I discovered that the anti-candida medication nystatin significantly improved my heartburn and fatigue. Also, the elimination of sugar from my diet was extremely helpful. This improvement, and my symptoms and history, matched the description of candida-related complex (especially the fact my symptoms started after I took tetracycling long-term, known to cause an increase in candida in the gastrointestinal tract). My illness appears to be caused by overgrowth of candida in the GI tract, described as "chronic candida" or Candida-Related Complex (CRC). This syndrome has not been scientifically defined, and thus has no official diagnostic criteria. I hope to see research done to establish the existence of this syndrome.

Unfortunately, it was too late for my illness to be reversed by nystatin and diet (I tried the prescription antifungal "diflucan", too, but it did not help). I also tried a large selection of supplements, such as caprylic acid, garlic, and probiotics, but they only made a trivial difference in my symptoms.

Around 1994, I began reading medical literature about the gastrointestinal microflora and probiotic bacteria. I sought out probiotics which showed possible benefits in the medical literature, experimenting with dozens of probiotic strains. I found one to be significantly helpful, Lactobacillus GG. It reduces my fatigue, which fits with the medical research showing it helps improve intestinal permeability.

Today, I remain ill and extremely limited by the fatigue this illness causes. I have been this way from 1987 to 2008, 22 years, over half my life. I find coping with the illness psychologicaly, emotionally, and financially to be as difficult as the symptoms themselves:

• the frustration and disssapointment of not being able to accomplish what you want
• the financial hardship of having an extremely limited ability to work
• doctors refusing to provide what little treatment is available, because the illness is not officially recognized
• Other people unable to understand your illness, which has no outward symptoms and is hard to understand

I have continued to try any probiotic which has medical research behind it, but not yet found another one which is beneficial for me. I recently tried Daktarin oral miconazole gel, but didn't experience a significant benefit. I have not yet tried Sporanox or Nizoral, party because I am unable to get them prescribed locally.

On the plus side, while I still struggle with the above symptoms daily, I have a beautiful wife and child, my own business, and I find research being done on intestial permeability and probiotics might lead to a treatment someday.

My own medical evaluations

Several endoscopies have shown I have esophagitis and gastritis. Around 1995, I requested a workup for malabsorption which showed I had a serum B₁₂ deficiency, fat malabsorption (based upon quantitative fecal fat), and mild carbohydrate malabsorption (based upon a D-xylose test).

There is no conventional medical diagnosis for these abnormal test results. Possible explanations like celiac sprue, giardia, hypothyroidism have been ruled out. The symptoms of malabsorption and positive tests for the same are officially a "coincidence", with no underlying medical cause.

My subjective symptoms like fatigue, for which there is no medical test, were on occasion diagnosed as undifferentiated somatoform disorder, a psychiatric diagnosis based on the absence of a conventional medical diagnosis. This assumes that medicine is both a complete science (all medical disorders are already known and discovered), and practitioners never miss a diagnosis. In truth the FDA reports that we don't know all of the adverse drug reactions to drugs currently on the market, and my illness appears to be an adverse reaction to the tetracyling I was taking when it started.

I know of other people with a history similar to the above, with the key features being identical. I would like to see epidemiological research done to establish what appears to be a unique pattern of symptoms.

Disclaimer: Information on this site, including comments on medical treatments, is not intended as medical advice to visitors. It should be evaluated critically and should not take the place of medical advice from a licensed healthcare professional.